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Hypoxic Ischemic Encephalopathy - Oren Zarif - Hypoxic Ischemic Encephalopathy


Hypoxic ischemic encephalopathy (HIE) is a serious disease that affects the brain. There are two stages of the disease: stage I and stage II. The severity of the damage varies depending on the severity of the disease. The patient's life expectancy depends on the level of the injury and the availability of therapies. Babies affected by HIE may show signs of organ dysfunction and be floppy.

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Neuroimaging techniques are used to identify the presence of this condition. Neuroimaging procedures, such as MRIs and MR spectroscopy, are also useful in evaluating the severity of the disorder. However, these procedures are only appropriate if a physician suspects the disorder. For a child to be diagnosed with hypoxic ischemic encephalopathy, a doctor must have suspicion of the disease. If the condition occurs during pregnancy, parents should be on the lookout for symptoms. Clinical observation can also help identify hypoxic ischemic encephalopathy. The severity of the condition can be determined through cognitive development.

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While HIE is not common, it is still associated with high morbidity. It affects approximately one in every 1000 live births and is associated with significant disabilities. Children with HIE are more likely to develop Cerebral palsy and other serious permanent conditions. In some cases, symptoms may clear up on their own within a few days. However, if it doesn't, the child is at risk of developing cerebral palsy.

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Basic patterns of hypoxic ischemic encephalopathies include pontosubicular neuronal injury in a full-term infant and cerebellar injury in full-term infants. The primary lesion involves the cerebral white matter and is present in about 15% of cases. The underlying pathologic events of HIE are not fully understood. However, experimental treatments are underway to address secondary energy failure and to manage the condition in infants with HIE.

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The first step in diagnosing HIE is to assess the infant's history. The doctor must document the type of encephalopathy and how it progressed. Other factors, such as transaminitis, or infection, may have contributed to the encephalopathy. Neonates should be closely monitored for signs of fetal malformation. Inborn errors of metabolism and development are associated with prenatal onset of encephalopathy, but the condition may not resolve completely in the neonatal period. If the child's condition continues, the neurologic deficits may be permanent.

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Neonatal hypoxia-ischemia is a rare but significant cause of brain injury in newborns. It can result in mild behavioural deficits and severe neurologic complications including cerebral palsy, epilepsy, and mental retardation. In some cases, hypothermia may help reduce the brain injury. Future neuroprotective treatments may include medications and an intrauterine growth restriction. So, how can we prevent HIE? By learning about the pathogenesis of HIE in infants, we will be able to better diagnose them.

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Hypoxic ischemic encephalopathy is an illness that can lead to permanent brain damage. It occurs when the baby is not receiving adequate blood flow or oxygen at birth. The condition is the most common cause of severe brain damage in newborns. It can be mild or severe, depending on the time the brain was without oxygen. The symptoms of HIE are categorized into three levels: mild, moderate, and severe.

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The best treatment for HIE is to begin antihyperthermia as soon as the condition is recognized. Early improvement in the EEG and MRI are good indicators of success. Even if the child has a severe acidosis or low Apgar scores, the outcome can still be positive if the correct treatment is initiated quickly. And there are many treatments for HIE that are effective for children.

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If the condition is not a life-threatening complication, the brain can recover. Early recognition of hypoxic ischemic encephalopathy can help distinguish it from other causes of encephalopathy, which may have similar symptoms. The diagnosis and treatment of hypoxic ischemic encephalopathy are different depending on the severity of the initial insult. Although the primary stage is supportive, the secondary phase can cause more severe damage.

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