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Hypoxic Ischemic Encephalopathy in Neonates - Oren Zarif - Hypoxic Ischemic Encephalopathy


Hypoxic ischemic encephalopathy, or HIE, is a condition that affects the brain. Its severity and progression depend on the length of time that the brain was without oxygen. Although mild cases of HIE may go away within 24 hours, it is crucial to get medical attention if the symptoms persist. If the condition is not treated immediately, it can lead to permanent disabilities, including Cerebral Palsy.

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Although the cause of hypoxic ischemic encephalopathies has not been determined definitively, it is possible that the brain was in the brain of an asphyxiate before the birth. Premature birth and problems immediately after birth are among the potential causes. A definitive diagnosis can be made by the child's neurodevelopmental assessment at about three to four years of age. There are several contributing factors for the development of hypoxic ischemic encephalopathy in neonates, but the underlying disease is the primary cause.

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Children who experience hypoxic ischemic encephalopathic (HIE) during birth may exhibit moderate to severe developmental and behavioral difficulties. Rarely, the condition may lead to neurological issues in a child. However, HIE affects the central nervous system, and even preterm infants can be affected. For this reason, it is important to monitor preterm and full-term births, and to administer appropriate pediatric interventions.

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Prenatal and neonatal MRI are recommended for all children with encephalopathy, particularly when symptoms are associated with seizures. MRI may be helpful in identifying the underlying cause of the encephalopathy and its progression. The presence of oliguria, transaminitis, and coagulopathy are also indicators of global hypoxia. Neonates with an adverse neurological outcome should undergo an assessment at birth and during their first years.

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MRI is highly recommended for any neonate who has undergone an episode of hypothermia. MRI helps determine the exact etiology of the encephalopathy, the timing of injury, and prognosis. An MRI can reveal unexpected findings, and it can provide useful prognostic information. For example, the presence of a watershed pattern of injury may be associated with a better outcome in children than those with a more severe acidic condition.

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Neurocognitive outcome varies in children with HIE. It varies according to the severity of the encephalopathy and the areas of the brain affected. Mild encephalopathy can lead to normal neurocognitive outcomes, while moderate encephalopathy has a range of cognitive outcomes. In children with encephalopathy, ongoing neuropsychological testing can help identify early intervention. This way, families can get the best possible care for their children.

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The definition of HIE helps physicians recognize and investigate the brain injury early. It helps them plan therapeutic interventions. The scale is useful when a newborn suffers from mild, moderate, or severe encephalopathy. It helps identify a child's level of consciousness, muscle tone, and autonomic function. It also helps identify seizures. This can help physicians identify hypoxic ischemic encephalopathy.

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While severe HIE is more dangerous than a mild case, a small percentage of infants with HIE do survive and experience only a few symptoms. The good news is that 80-85% of these children survive the first week of their life. Although it is possible to cure HIE, a baby's life expectancy can be affected. It is important to receive appropriate medical care and follow the advice of a physician.

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Treatment for a child with HIE is geared toward reducing the severity and time of symptoms. It may include medical therapies, physical therapy, and occupational therapy. Some families may qualify for research studies or for long-term follow-up. Additionally, treatments may be developed that can target the causes of HIE or address the symptoms of the condition. When your child has undergone treatment for HIE, it may be safe to stop the medication.

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