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What is Cerebral Infarction? - Oren Zarif - Cerebral Infarction


A cerebral infarction is a type of ischemia, resulting in persistent focal neurologic deficit. It is also called a brainstem syndrome. Other than the stroke that can result, cerebral infarction can be caused by various other conditions. The symptoms of cerebral infarction are determined by the part of the brain affected. Depending on the location, some common symptoms include weakness of one side of the body, loss of sensation, abnormal pupil dilation, abnormal eye movement, and headache. A cerebral infarction can also result in slurred speech and aggravate reflexes.

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Histology is a useful tool to detect cerebral infarction. This tissue shows a gray-white hematoxylin-eosin (H&E) stains. Histological changes in this tissue include cytoplasmic eosinophilia, perineuronal vacuolation, and shrinking of the brain. A cerebral infarction may also be caused by a cerebral embolus. The breaking up of an embolus restores blood flow to the ischemic region. The hemorrhagic infarction, on the other hand, results from the leakage of blood through damaged blood vessels.

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The study reported on the etiology of cerebral infarction in young adults. The most common causes were hematologic conditions and cardiac embolism, but nearly a third of first strokes had no identifiable cause. The study also noted that some patients did have recurrent stroke. The authors conclude that vascular risk factors increase the risk of cerebral infarction and must be addressed. The study of young adults is a timely one.

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If a thrombus occluding an artery is causing a cerebral infarction, definitive therapy is recommended. One type of therapy is thrombolysis, which dissolves clots in the brain, or thrombectomy. In both cases, the goal of definitive therapy is the same: to increase blood flow to the brain. Using either of these methods will help ensure that brain cells are spared from death.

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Cerebral infarction can be caused by a number of medical conditions. Atherosclerosis reduces blood flow to the brain, causing a reduced supply of oxygen and other vital nutrients. As a result, parts of the brain die because the brain can no longer receive the blood it needs. There are various types of cerebral infarction. Luckily, there is an underlying medical condition that can lead to a stroke.

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Neuroimaging results of 28 patients are summarized in Table 3. A small number of patients had single or multiple infarctions in the basal ganglia. The remainder of patients had multiple infarctions, which can occur in the internal capsule, the cerebellum, and the brain. Nineteen of the patients had obstructive or communicating hydrocephalus. Twenty-eight patients had TBMs. The other three patients had space-occupying lesions and miliary patterns.

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There are other ways to recognize a cerebral infarction. For instance, patients with burns may experience cerebral infarction if there are signs of fungal infection in the bloodstream. Additionally, patients with invasive candidiasis should be evaluated for fungal invading cerebral blood vessels. If the patient had signs of sepsis, there is a high probability that he or she has a fungal infection.

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Chronic meningitis is the most common cause of cerebral infarction. Patients with TBM or cryptococcal meningitis usually have a high mortality rate. Symptoms of TBM are the same, but extracranial involvement is more common. These complications are often associated with neurological problems, including hydrocephalus and seizures. In either case, the diagnosis must be made quickly in order to maximize a patient's survival. An early diagnosis of cerebral infarction is vital in minimizing the risk of further cerebral ischaemia.

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Another type of cerebrovascular disorder is transient ischemic attack. It is a type of stroke characterized by an abrupt loss of blood circulation to the brain. A stroke of this type is more common than hemorrhagic stroke. Depending on the location of the infarct, it may appear as a single or multiple stroke. However, if the infarct is in an artery of a large size, it may be called a "large-vessel infarction." The CTA is highly accurate in detecting stenosis, and it accounts for more than one-third of all cases of ischemic stroke in dogs.

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While ischemia-induced brain damage is usually irreversible, massive infarcts can still pose a challenge for doctors. In this setting, thrombolysis, anticoagulation therapy, and other methods of treatment may not be helpful. In cases of acute massive cerebral infarction, a new treatment called nimodipine may be the best option. This drug crosses the blood-brain barrier and selectively acts on intracranial blood vessels. Although the risks of this treatment remain unknown, it is an excellent alternative to a traumatic brain injury.

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